Methoxyvone™

5-methyl-7-methoxy-isoflavone (U.S. patent 4,163,746)

Methoxyvone™ aka the “Anabolic Silver Bullet” is an oral anabolic agent that can significantly affect protein metabolism in the body. Methoxyvone™ initiates protein synthesis and this effect triggers positive nitrogen stability helping increase protein synthesis and thus builds up skeletal muscle mass. The search for a supplement that would produce the highly anabolic and sought-after effects of faster muscle growth, recovery, and lean muscle increases, yet avoid the androgenic steroid-like side effects has been an impossible task? Many of the flavones studied over the past several decades would show excellent results in animals and even some in humans via non oral routes. This dilemma has been overcome with LG Sciences Cyclosome™ Technology that causes Methoxyvone™ to have a 20 fold increase in absorption versus regular encapsulated 5-methyl-7-methoxy-isoflavone. There have been several products on the market in the past that only got mediocre results. Unfortunately, without an effective system like LG’s Cyclosome™ Technology, Methoxyvone™ is not well absorbed and therefore could be rendered ineffective. Please be sure that any isoflavone or 5-methyl-7-methoxy-isoflavone product you purchase has a scientifically sound method to drastically increase its bio-availability.

SUPPLEMENT FACTS

THE SCIENCE

Several of the flavones that held promise were originally discovered and patented by a Hungarian company who held a patent that did not expire until 1997. Two of these compounds were 5-methyl-7-methoxy-isoflavone (U.S. patent 4,163,746) and 7-Isopropoxyisoflavone have been shown to increase protein synthesis and increase lean mass, but they also reduced body fat, promoted endurance, an increased state of vitality, and increased the body’s ability to use oxygen! In other words, these are the definition of the ideal anabolic supplements… Scientific studies give evidence to support these results. In a nutshell, methoxyisoflavone and ipriflavone are non-hormonal anabolic / anti-catabolic compounds. These powerful flavones have been shown to decrease cortisol levels, increase protein synthesis, and improve overall recovery from exercise.

Phytomedicines, complex chemical mixtures prepared from plants, have been used in medicine since ancient times and continue to have widespread popular use. Most of the bioactive constituents of herbal drugs are water soluble molecules However, water soluble phyto-constituents like many flavonoids are poorly absorbed either due to their multiple ring large size molecules which cannot be absorbed by simple diffusion, or due to their poor miscibility with oils and other lipids, severely limiting their ability to pass across the lipid-rich outer membranes of the enterocytes of the small intestine. Water-soluble constituent molecules (mainly polyphenols) can be converted into lipid-compatible molecular complexes, which are called Cyclosome™.

Cyclosome™ are more bioavailable as compared to simple herbal extracts owing to their enhanced capacity to cross the lipid rich bio membranes and finally reaching the blood. Phospholipids are complex molecules that are used in all known life forms to make cell membranes. They are cell membrane building blocks, making up the matrix into which fit a large variety of proteins that are enzymes, transport proteins, receptors, and other biological energy converters. In humans and other higher animals the phospholipids are also employed as natural digestive aids and as carriers for both fat-miscible and water-miscible nutrients. They are miscible both in water and in oil/lipid environments, and are well absorbed orally. Phospholipids are small lipid molecules in which the glycerol is bonded only to two fatty acids, instead of three as in triglycerides, with the remaining site occupied by a phosphate group. The phospholipid mainly employed to make cyclosomes, is phosphatidylcholine, derived from soybean.

In order to fully understand the power of Methoxyvone™, however; we must start with the first anabolic flavone compound to make big waves: 7-Isopropoxyisoflavone or Ipriflavone. The research was aimed toward finding a nutrient partitioning agent able to transport much needed nutrients away from fat (adipose) tissue and toward muscle (proteinaceous) tissue. While most companies were pouring millions of dollars into new more effective anabolic steroids, one company in Hungary, named Chinoin, decided to look for a non-steroidal compound that would have the positive effects of Anabolics but without the negative characteristics. Chinoin (Hungarian pharmaceutical company), a leader in flavonoid research and knowledge, developed Ipriflavone in the early 1970’s. After over 10 years of research, they discovered Methoxyvone. Methoxyvone was the end result of Chinoin’s extensive research on anabolic isoflavones.

Said slightly in another way, Methoxyvone is three times more potent than ipriflavone in term of increasing lean body mass, decreasing adipose stores, increasing endurance, etc. Although developed in the last millennium, it is destined to become one of the best ergogens in this new millennium. LG’s excitement for this product stems not only from the published data on Methoxyvone but also based on the plethora of correspondence had with Chinoin. According to their research department, they performed a barrage of experiments to examine its anabolic potency. To give an idea of its capabilities, Methoxyvone was studied to see whether it could antagonize the catabolic effects of gluccocorticoids, i.e. cortisol. For those of you who don’t know already, gluccocortidoids are one of the most catabolic entities (especially relating to proteinaceous tissue such as muscle) in the human body. Although they do have some very important beneficial properties such as anti-inflammation, when it comes to gaining muscle and losing fat they are your worst nightmare. Gluccocorticoids are always in your body and they are always wreaking havoc. They are produced in the adrenal cortex, released into the blood and attach to various receptors in nearly every tissue in the body. Methoxyvone, on the other hand, almost completely antagonized cortisol’s effects at lower dosages and did a good job of attenuating them at higher dosages.

Studied during the same time period as Ipriflavone, Methoxyisoflavone’s scientific data definitely impressed the government to justify issuing a patent for it. As it turns out, Methoxyisoflavone is perhaps the most potent legal anabolic compound with no side effects. Some of the findings include:

1. In the same test used for Ipriflavone, results confirmed that Methoxyisoflavone was more anabolic than both Ipriflavone and anabolic steroids! All the while, no androgenic side effects occurred whatsoever with Methoxyisoflavone.
2. Again, regardless of species, lean body mass increased significantly within 30 days accompanied by an increased state of vitality; while producing no androgenic effects and no endocrine tissue alteration! In terms we can all appreciate, this compound has been shown to increase muscle mass and size, while also making you feel better.
3. Cortisol levels were reduced in wasting patients, while phosphorus, calcium, potassium, and nitrogen levels increased considerably. What does all this mean? Simple-More Muscle!

 
Thus, a few years ago when I started researching these anabolic isoflavones, I was limited only to Iproflavone because of cost and availability. Although I was impressed with Ipriflavone I had my sights set on Methoxyvone.

Anabolic or anti-catabolic compounds are called nutrient partitioning agents. Normally, when you ingest calories a certain portion of them are used for immediate needs, others are partitioned off into fat stores, and still others are used to build proteinaceous tissues. A nutrient partitioning agent will take more of those calories and shuttle them into proteinaceous tissues. Therefore, a nutrient partitioning agent or anabolic compound will make you leaner and more muscular if your calorie intake remains the same but it won’t cause you to gain weight. To gain weight you must either consume more calories or slow down your metabolism. The great thing about taking an anabolic is that if you ingest more calories, it will cause a preferential increase in muscle mass.

Attention: These products are not anabolic steroids and all claims are theories. LG Sciences’ products will only assist you in reaching your fitness goals. Muscle and weight gain are the result of hard exercise and proper diet, supplements are not a replacement.

SUGGESTED USE

DIRECTIONS: Take 2 tablets spread out during the day with at least 6 hours between doses. Do not exceed recommended dosage.